Test
Applications: Functional, In vitro assay, In vivo assay, Ligand Activation
Target | Pam3CSK4, TLR1 and TLR2 Ligand |
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Content And Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Concentration | 0.5 mg/mL |
For Use With (Application) | Activation of TLR1 and TLR2 heterodimer. Stimulation of TLR1 and TLR2 has been reported with 10 to 100ng/mL. Use in vitro assay reported in scientific literature (PMID: 24105263) Use in functional reported in scientific literature (PMID 25511699). Use in In-vivo reported in scientific literature (PMID 25466255). Use in ligand activation reported in multiple pieces scientific literature. |
Species | Human/Mouse |
Mouse Monoclonal Antibody
May be dissolved in DMSO (200 mg/mL); or ethanol (10 mg/mL, warm)
Content And Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
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Donor Source | Synthetic |
CAS | 879085-55-9 |
Purity or Quality Grade | >80% by SDS-PAGE and Coomassie blue staining |
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Gene Alias | double stranded RNA activated protein kinase, EC 2.7.11.1, eIF-2A protein kinase 2, EIF2AK1, eukaryotic translation initiation factor 2-alpha kinase 2P1/eIF-2A protein kinase, interferon-induced, double-stranded RNA-activated protein kinase, interferon-inducible double stranded RNA dependent, interferon-inducible elF2alpha kinase, Interferon-inducible RNA-dependent protein kinase, PKRp68 kinase, PRKRMGC126524, Protein kinase RNA-activated |
Molecular Weight (g/mol) | MolecularWeight-theroretical: 36.74 kDa |
Gene ID (Entrez) | 5610 |
Formulation | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer. |
Gene Symbol | EIF2AK2 |
Research Category | Apoptosis, Signal Transduction |
Storage Requirements | Store at -80°C. Avoid freeze-thaw cycles. |
For Use With (Application) | Western Blot,ELISA,SDS-PAGE,Protein Array,Immunoaffinity Purification |
Protein | PKR |
Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Applications: Functional, In vitro assay, Ligand Activation
Target | Imiquimod, TLR7 ligand |
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Content And Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
Formulation | C14H16N4, HCl |
Concentration | 2.5 mg/mL |
For Use With (Application) | This product is useful for activation of TLR7 and stimulation of TLR7 has been achieved with 5 to 10μL. Use in ligand activation, functional, and in vitro reported in scientific literature (PMID 25957979) |
Species | Human/Mouse |
Rabbit Monoclonal Antibody
Content And Storage | Store at 4&drg;C. Do not freeze. |
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Target Species | Human |
Host Species | Rabbit |
Conjugate | Unconjugated |
Applications | Immunohistochemistry (Paraffin) |
Form | Purified |
Isotype | IgG κ |
Research Discipline | Adaptive Immunity, Cell Biology, Cellular Markers, Cellular Signaling, Cytokine Research, Glia Markers, Hematopoietic Stem Cell Markers, Immunology, MAP Kinase Signaling, Mast Cell Markers, Mesenchymal Stem Cell Markers, Microglia Markers, Modulation of DNA Pools, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Signal Transduction, Stem Cell Markers |
Concentration | 0.2 mg/ml |
Antigen | CD45RA |
Regulatory Status | RUO |
Purification Method | Protein A or G purified |
Dilution | Immunohistochemistry-Paraffin 1-2 μg/mL |
Gene Alias | B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide |
Gene ID (Entrez) | 5788 |
Formulation | 10mM PBS with 0.05% BSA |
Immunogen | Recombinant fragment (around aa1-600) of human CD45RA protein (extracellular domain) |
Classification | Monoclonal |
Primary or Secondary | Primary |
Clone | PTPRC/4367R |