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  7. 17514346

Thermo Scientific™ EZ-Link™ TFP Ester-PEG4-DBCO

An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules.

Brand:  Thermo Scientific™ C20039

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Product Code. 17514346

  • 222.00€ / 25mg

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Description

Description

  • An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications
  • The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules
  • Once a protein or (bio)molecule is DBCO labeled, it can undergo a copper-free azide-alkyne cycloaddition reaction to form a stable triazole linkage with an azide labeled coupling partner
  • Can be used to create diverse conjugates with the biorthogonal coupling between an alkyne and azide (supplied separately)
  • The coupling or crosslinking procedure is typically done in two steps
    • First, a protein or amine containing molecule is labeled with a DBCO group and excess crosslinker is removed
    • Second, an azide containing moiety (prepared independently) is introduced into the same system as the DBCO moiety
    • Labeling occurs under biological conditions without the introduction of any additional reagents such as a copper catalyst
  • Ragent readily dissolves in water-miscible solvents for dilution into aqueous reaction mixtures
  • TFP esters are more hydrolytically stable than NHS esters
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-Azide
TFP Ester-PEG4-DBCO
Yes
Upon receipt store desiccated at -20°C.
Wet Ice
Chemical Labeling
TFP Ester, DBCO
Solid
DMF, DMSO
No
No
714.7
17.9 Å
Not determined
EZ-Link™ No-Weigh™
Heterobifunctional
Medium (10 to 30 Å)
25 mg
Standard, Single-use
Crosslinker
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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberZJ401996 Certificate TypeCertificate of Analysis Date16/12/2024 Catalog NumberC20039
Lot NumberZF393663 Certificate TypeCertificate of Analysis Date15/06/2024 Catalog NumberC20039
Lot NumberZB389606 Certificate TypeCertificate of Analysis Date09/02/2024 Catalog NumberC20039
Lot NumberYL383183 Certificate TypeCertificate of Analysis Date25/01/2024 Catalog NumberC20039
Lot NumberYE371655 Certificate TypeCertificate of Analysis Date22/06/2023 Catalog NumberC20039
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Thermo Scientific™ EZ-Link™ TFP Ester-PEG4-DBCO > 25 mg

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