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Thermo Scientific™ Pierce™ Premium Grade Sulfo-NHS (N-hydroxysulfosuccinimide)
Optimize applications where product integrity and risk minimization are paramount with our highest quality formulation of this N-hydroxysuccinimide modification reagent.
Brand: Thermo Scientific™ PG82071
This item is not returnable.
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Description
Optimize applications where product integrity and risk minimization are paramount with the specially characterized Thermo Scientific™ Pierce™ Premium Grade Sulfo-NHS, our highest quality formulation of this N-hydroxysuccinimide chemical modification reagent.
Thermo Scientific Pierce Premium Grade Sulfo-NHS is our highest quality formulation of this N-hydroxysuccinimide chemical modification reagent, specially characterized for applications where product integrity and risk minimization are paramount.
Compared to the standard grade product, Premium Grade Sulfo-NHS provides more clearly defined quality and product support by including (a) increased analytical testing and product characterization, (b) greater batch-specific information and quality assurance review, (c) extensive lot sample retention and (d) change control notification. Sulfo-NHS (N-hydroxysulfosuccinimide) enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates (–COOH) for conjugation with primary amines (–NH2). Derivatives are easily synthesized by mixing the sulfo-NHS with a carboxyl-containing molecule and a dehydrating agent such as the carbodiimide EDC (EDAC). The method is the basis for generating many types of protein labeling reagents, including amine-reactive fluorescent dyes, biotin affinity tags and pegylation compounds.
Highlights:- Sulfo-NHS – use with EDC crosslinker to prepare amine-reactive NHS ester reagents
- High quality – identity and purity confirmed by several tests, including quantitative NMR
- Product integrity – enhanced level of testing and characterization compared to standard grade
- Lot retention – ample supply of past lots retained to ensure future process testing
- Change management – Change Control Notification (CCN) service
- Consistent manufacture – batch-specific manufacturing documentation review
- Improve efficiency of EDC coupling reactions
- Convert carboxyls to amine-reactive sulfo-NHS esters
- Membrane-impermable for cell surface labeling
- Crosslink proteins to carboxyl-coated beads or surfaces more efficiently
- Activate nanoparticles with amine-reactive sulfo-NHS esters
Specifications
| Amine-Carboxyl | |
| Sulfo-NHS | |
| No | |
| No | |
| Pierce™ | |
| Heterobifunctional | |
| Short (<10 Å) | |
| 500 mg | |
| Standard, Single-use, Premium-grade | |
| Crosslinker |
| No | |
| 217.13 | |
| Upon receipt store at 4°C. | |
| Ambient | |
| Chemical Labeling | |
| Carbodiimide | |
| Powder | |
| Water | |
| Yes |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Pierce Premium Grade Sulfo-NHS (N-hydroxysulfosuccinimide)
Signal Word
- Warning
Hazard Category
- Serious eye damage/eye irritation Category 2
- Flammable liquid Category 3
Hazard Statement
- H226-Flammable liquid and vapour.
- H319-Causes serious eye irritation.
Precautionary Statement
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
- P264-Wash hands thoroughly after handling.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P337+P313-If eye irritation persists: Get medical advice/attention.
- P403+P233-Store in a well-ventilated place. Keep container tightly closed.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : ethanol
For Research Use Only. Not for use in diagnostic procedures.