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Thermo Scientific™ Pierce™ Premium Grade Sulfo-NHS (N-hydroxysulfosuccinimide)

Optimize applications where product integrity and risk minimization are paramount with our highest quality formulation of this N-hydroxysuccinimide modification reagent.

Brand:  Thermo Scientific™ PG82071


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Product Code. 15215763

  • 264.00€ / 500mg
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Description

Description

Optimize applications where product integrity and risk minimization are paramount with the specially characterized Thermo Scientific™ Pierce™ Premium Grade Sulfo-NHS, our highest quality formulation of this N-hydroxysuccinimide chemical modification reagent.

Thermo Scientific Pierce Premium Grade Sulfo-NHS is our highest quality formulation of this N-hydroxysuccinimide chemical modification reagent, specially characterized for applications where product integrity and risk minimization are paramount.

Compared to the standard grade product, Premium Grade Sulfo-NHS provides more clearly defined quality and product support by including (a) increased analytical testing and product characterization, (b) greater batch-specific information and quality assurance review, (c) extensive lot sample retention and (d) change control notification. Sulfo-NHS (N-hydroxysulfosuccinimide) enables control and modification of carbodiimide crosslinking reactions involving activation of carboxylates (–COOH) for conjugation with primary amines (–NH2). Derivatives are easily synthesized by mixing the sulfo-NHS with a carboxyl-containing molecule and a dehydrating agent such as the carbodiimide EDC (EDAC). The method is the basis for generating many types of protein labeling reagents, including amine-reactive fluorescent dyes, biotin affinity tags and pegylation compounds.

Highlights:
  • Sulfo-NHS – use with EDC crosslinker to prepare amine-reactive NHS ester reagents
  • High quality – identity and purity confirmed by several tests, including quantitative NMR
  • Product integrity – enhanced level of testing and characterization compared to standard grade
  • Lot retention – ample supply of past lots retained to ensure future process testing
  • Change management – Change Control Notification (CCN) service
  • Consistent manufacture – batch-specific manufacturing documentation review
Applications:
  • Improve efficiency of EDC coupling reactions
  • Convert carboxyls to amine-reactive sulfo-NHS esters
  • Membrane-impermable for cell surface labeling
  • Crosslink proteins to carboxyl-coated beads or surfaces more efficiently
  • Activate nanoparticles with amine-reactive sulfo-NHS esters
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-Carboxyl
217.13
Upon receipt store at 4°C.
Ambient
Chemical Labeling
Carbodiimide
Powder
Water
Yes
No
No
No
Pierce™
Heterobifunctional
Short (<10 Å)
500 mg
Standard, Single-use, Premium-grade
Crosslinker
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Safety and Handling

Safety and Handling

Product Identifier
  • Pierce Premium Grade Sulfo-NHS (N-hydroxysulfosuccinimide)

Signal Word
  • Warning

Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Flammable liquid Category 3

Hazard Statement
  • H226-Flammable liquid and vapour.
  • H319-Causes serious eye irritation.

Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
  • P264-Wash hands thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P403+P233-Store in a well-ventilated place. Keep container tightly closed.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information
  • MIXTURE LIST-Contains : ethanol

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For Research Use Only. Not for use in diagnostic procedures.