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Thermo Scientific™ NHS (N-hydroxysuccinimide)
Prepare amine-reactive NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysuccinimide, CAS 6066-82-6.
Brand: Thermo Scientific™ 24500
This item is not returnable.
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Description
Thermo Scientific™ Pierce NHS is pure N-hydroxysuccinimide, the essential compound needed to prepare amine-reactive NHS-ester crosslinkers or to enhance conjugation efficiencies when using the carbodiimide EDC.
Highlights:
- Form an acyl amino ester with carboxyl groups when used the EDC
- NHS-activated molecule reacts efficiently with primary amines, resulting in stable amide bond
- Allows for two-step EDC reactions between carboxyl- and amine-containing molecules
- NHS-activated molecule can be stabilized by drying, allowing manufacture of amine-reactive probes and surfaces
- Reactive groups: NHS
- Reactive toward: amino groups (upon activation of carboxylates)
Specifications
Amine-Carboxyl | |
NHS | |
No | |
Not determined | |
Pierce™ | |
Heterobifunctional | |
Short (<10 Å) | |
25 g | |
Standard | |
Crosslinker |
No | |
115.09 | |
Upon receipt store at 4°C. | |
Ambient | |
Chemical Labeling | |
Carbodiimide | |
Powder | |
Water | |
Yes |
For Research Use Only. Not for use in diagnostic procedures.