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Vinculin Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen Vinculin
Concentration 0.4 mg/mL
Applications Western Blot, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16864955
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Proteintech
26520-1-AP-20UL
20 μL
145.00€
20µL
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16854955
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Proteintech
26520-1-AP-150UL
150 μL
410.00€
150µL
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Description

Description

Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions. It functions as one of several interacting proteins involved in anchoring F-actin to the membrane. It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques. In the assembly of adhesion plaques, the beta subunit of integrin binds to talin. Talin binds to vinculin that interacts with alpha-actinin and possibly with itself. Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system. Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.
Specifications

Specifications

Vinculin
Western Blot, Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry
Unconjugated
Rabbit
Human, Mouse
P18206, Q64727
22330, 7414
Vinculin Fusion Protein Ag24942
Primary
-20°C
VCL
0.4 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CMD1W, Metavinculin, MVCL, VCL, Vinculin
VCL
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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Vinculin Rabbit anti-Human, Mouse, Polyclonal, Proteintech

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