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Trimethylacetyl chloride, 98+%, Thermo Scientific Chemicals

26.93€ - 236.18€

Chemical Identifiers

CAS 3282-30-2
Molecular Formula C5H9ClO
Molecular Weight (g/mol) 120.58
MDL Number MFCD00000709
InChI Key JVSFQJZRHXAUGT-UHFFFAOYSA-N
Synonym pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride
PubChem CID 62493
IUPAC Name 2,2-dimethylpropanoyl chloride
SMILES CC(C)(C)C(Cl)=O
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Products 3
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Product Code Brand Quantity Price Quantity & Availability  
11680212
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Thermo Scientific Alfa Aesar
A15051.AE
100 mL
26.93€
100mL
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11431960
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Thermo Scientific Alfa Aesar
A15051.AP
500 mL
67.13€
500mL
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11441960
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Thermo Scientific Alfa Aesar
A15051.0F
2500 mL
236.18€
2500mL
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Description

Description

Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible withalcohols, oxidizing agents and strong bases.
Specifications

Chemical Identifiers

3282-30-2
120.58
JVSFQJZRHXAUGT-UHFFFAOYSA-N
62493
CC(C)(C)C(Cl)=O
C5H9ClO
MFCD00000709
pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride
2,2-dimethylpropanoyl chloride

Specifications

3282-30-2
0.985
8°C (46°F)
C5H9ClO
MFCD00000709
385668
pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride
JVSFQJZRHXAUGT-UHFFFAOYSA-N
2,2-dimethylpropanoyl chloride
62493
≥98%
-57°C
105°C to 106°C
Pungent
1.412
UN2438
Moisture sensitive
Miscible with acetonitrile.
CC(C)(C)C(Cl)=O
120.58
120.58
Trimethylacetyl chloride
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Safety and Handling

Safety and Handling

GHS H Statement
H225-H330-H314-H318-H302
Highly flammable liquid and vapour.
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.

P210-P233-P234-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P390-P501c

H225-H290-H302-H314-H330

missing translation for 'dotInformation' : Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TRIMETHYLACETYL CHLORIDE

missing translation for 'einecsNumber' : 221-921-6

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier
  • Trimethylacetyl chloride

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 2
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 1
  • Flammable liquid Category 2
  • Substances and mixtures corrosive to metals Category 1
  • Skin corrosion/irritation Category 1 B

Hazard Statement
  • H225-Highly flammable liquid and vapour.
  • H290-May be corrosive to metals.
  • H302-Harmful if swallowed.
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • H330-Fatal if inhaled.

Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.

Supplemental information
  • MIXTURE LIST-Contains : Pivaloyl chloride

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only