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Tocris Bioscience™ SAG
Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway
232.00€ - 820.00€
Specifications
| Purity | >99% |
|---|---|
| Product Type | SAG |
| Molecular Weight (g/mol) | 490.06 |
| Inhibitors | SAG |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18024052
|
Tocris Bioscience™
4366/10 |
10 mg |
820.00€
10mg |
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|
18709807
|
Tocris Bioscience™
4366/1 |
1 mg |
232.00€
1mg |
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Description
SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopamine (Cat. No. 1623) action at the Smo receptor. SAG potently activates the Hedgehog signaling pathway in Shh-light 2 cells (EC50 ∼ 3 nM) and nduces pathway activation independently of Ptch proteins. SAG is a putative inhibitor of a cellular component required for Hedgehog signaling and also enhances neuronal differentiation of iPSCs into dopaminergic neurons.SAG dihydrochloride (Cat. No. 6390) also available.
Specifications
| >99% | |
| SAG | |
| 490.06 | |
| SAG |
For Research Use Only
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