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Tocris Bioscience™ NS 9283
Positive allosteric modulator of α4β2 nAChRs
Brand: Tocris Bioscience™ 5112/50
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Description
NS 9283 is a positive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ∼60 fold without affecting the maximum efficacy (HEK293-hα4β2 cells). Reduces the rate of recovery from desensitization and slows the rate of deactivation. Displays a synergistic effect on the Emax when given with NS206 at 3α:2β receptors.Specifications
>99% | |
NS 9283 | |
NS 9283 |
50 mg | |
248.24 |
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