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Tocris Bioscience™ ML 162
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
188.00€ - 737.00€
Specifications
| Chemical Name or Material | 2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide |
|---|---|
| CAS | 1035072-16-2 |
| Target | Glutathione Peroxidase 4/GPX4 |
| Molecular Formula | C23H22Cl2N2O3S |
| Purity | 0.98 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30000030
|
Tocris Bioscience™
7821/10 |
10 mg |
188.00€
10mg |
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|
30000010
|
Tocris Bioscience™
7821/50 |
50 mg |
737.00€
50mg |
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Description
ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. It induces ferroptosis in vivo. It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).Specifications
| 2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide | |
| Glutathione Peroxidase 4/GPX4 | |
| 0.98 |
| 1035072-16-2 | |
| C23H22Cl2N2O3S |
Safety and Handling
Recommended Storage : Store at -20°C
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