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Tocris Bioscience™ ML 162

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

Brand:  Tocris Bioscience™ 7821/10

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Product Code. 30000030

  • 188.00€ / 10mg

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Description

Description

ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. It induces ferroptosis in vivo. It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).
Specifications

Specifications

2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
10 mg
C23H22Cl2N2O3S
1035072-16-2
Glutathione Peroxidase 4/GPX4
0.98
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