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Cytiva™ MabSelect™ VL Protein L Resin
The MabSelect™ VL resin is a protein L resin for affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
Brand: Cytiva™ 17542001
This item is not returnable.
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Description
MabSelect™ VL resin with a redesigned protein L ligand for high binding capacity and improved alkaline stability. For affinity capture of antibody Fabs, bispecifics, and other variants containing a kappa light chain.
- High dynamic binding capacity protein L resin for efficient capture of antibody Fabs, bispecifics, and variants containing a kappa light chain
- Stable when cleaned with 0.1 M NaOH, reducing risk for bioburden incidents
- Provides good resolution for product-related impurities in the capture of bispecific antibodies
As the diversity of antibody variants increases, so does the need for chromatography resins that can capture and purify these variants. As an alternative to protein A, protein L resin can be used to capture antibody Fabs, bispecific antibodies, and other molecules containing kappa variants of the variable light (VL) chain. Protein L binds human kappa light chain subtypes 1, 3, and 4 and mouse kappa light chain subtype 1.
Specifications
| 25 mL | |
| Alkaline Stabilized Protein L-derived (E. coli) | |
| 60 μm | |
| Antibody Affinity Chromatography |
| 300 cm/hr. | |
| 2 to 10 | |
| 2°C to 8°C, 20% Ethanol | |
| VL Protein L Resin |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- MabSelect VL, 25 ml
Signal Word
- Warning
Hazard Category
- Flammable liquid Category 3
Hazard Statement
- H226-Flammable liquid and vapour.
Precautionary Statement
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : ethanol
- UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.