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Tocris Bioscience™ L-755,507

Very potent and selective β3 partial agonist

Brand:  Tocris Bioscience™ 2197/50

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Product Code. 18075602

  • 987.00€ / 50mg

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Description

Description

L-755,507 is a potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). Stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9 nM). Enhances CRISPR-mediated homology-directed repair (HDR) efficiency 2-3-fold for large fragments and ∽9-fold for point mutations, in human induced pluripotent stem cells (iPSCs).
Specifications

Specifications

>98%
L-755,507
L-755,507
50 mg
584.73
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