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Kanamycin monosulfate, Cell Culture Grade, Thermo Scientific Chemicals Product Code.: 15463399
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Kanamycin monosulfate, Cell Culture Grade, Thermo Scientific Chemicals

Product Code. 15463399
5 g
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5 g
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Regulatory: A license is required to purchase this product; ROYAL DECREE OF 12 APRIL 1974.

Product Code. 15463399

Brand: Thermo Scientific Alfa Aesar J60668.06

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This item is not returnable. View return policy
Regulatory: A license is required to purchase this product; ROYAL DECREE OF 12 APRIL 1974.

Description

Kanamycin monosulfate, CAS # 25389-94-0, is an aminoglycoside sulfate salt with antibacterial activity.

Kanamycin monosulfate, is used as an aminoglycoside antibiotic. Kanamycin can be used as a selection agent in several types of isolation media.Kanamycin sulfate from Streptomyces kanamyceticus has been used in tissue culture media. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 100mg/mL.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Kanamycin monosulfate is the sulfate salt form of kanamycin A

• It was isolated from Streptomyces kanamyceticus

• This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence

Application

• Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species

• This compound is also involved in translating prokaryotic ribosomes

• In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated

Literature References

Patel, K. N.; Limgavkar, R. S.; Raval, H. G.; Patel, K. G.; Gandhi, T. R. High-Performance Liquid Chromatographic Determination of Cefalexin Monohydrate and Kanamycin Monosulfate with Precolumn Derivatization. J. Liq. Chromatogr. Related Technol. 2015, 38 (6), 716-721.

Chi, Z.; Rong, Y. J.; Li, Y.; Tang, M. J.; Chi, Z. M. Biosurfactins production by Bacillus amyloliquefaciens R3 and their antibacterial activity against multi-drug resistant pathogenic E. coli. Bioprocess. Biosyst. Eng. 2015, 38 (5), 853-861.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 25389-94-0
Molecular Formula C18H38N4O15S
Molecular Weight (g/mol) 582.575
MDL Number MFCD00070253
InChI Key OOYGSFOGFJDDHP-IZQIRFRQSA-N
Synonym Kanamycin A
PubChem CID 134129479
IUPAC Name (2R,3S,4S,5S,6R)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O

Specifications

Type Kanamycin Monosulfate
Physical Form Powder
Color White
Quantity 5 g
Merck Index 14,5281
Solubility Information Soluble in water at 10mg/ml
Formula Weight 582.58
Grade Cell Culture
Chemical Name or Material Kanamycin monosulfate

Safety and Handling

compliance-icons
Product Identifier
  • Kanamycin monosulfate, Cell Culture Grade
 Signal Word
  • Danger
 Hazard Category
  • Reproductive toxicity Category 1B
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1
 Hazard Statement
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H360FD-May damage fertility. May damage the unborn child.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .
 Supplemental information
  • MIXTURE LIST-Contains : Kanamycin sulphate
SDS

RUO – Research Use Only

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