Invitrogen™ Silencer™ Select Negative Control No. 1 siRNA

Description

• A non-targeting negative control siRNA with the same chemical modifications for enhanced efficacy as in other Silencer™ Select siRNAs
• Validated siRNA controls for optimizing siRNA experiments
• GAPDH Positive Control functionally tested in several common cell lines
• Negative Controls functionally proven to have minimal effects on cell proliferation and viability
• Include Silencer™ Select modifications for enhanced specificity
• For use in human, mouse, and rat cells
• Upon receipt, store siRNAs in a non-frost-free freezer at or below -20°C

What are Silencer™ Select siRNAs?

• Silencer™Select siRNAs are our next-generation siRNAs
• These siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemical modifications to yield siRNAs with unrivalled efficacy, potency, and specificity
• The result is fewer failed experiments due to poor silencing, and cleaner, more consistent phenotypic data

Silencer™ Select Negative Control siRNAs

• Negative control siRNAs are siRNAs with sequences that do not target any gene product
• They are essential for determining the effects of siRNA delivery and for providing a baseline to compare siRNA-treated samples
• These negative control siRNAs have been tested by microarray analysis and shown to have minimal effects on gene expression
• In addition, these two controls have been tested in multi-parametric, cell-based assays and are proven to have no significant effect on cell proliferation, viability, or morphology in the cell lines tested