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Gibco™ Human Fractalkine (CX3CL1) Recombinant Protein, PeproTech®
Recombinant Protein
Brand: Gibco™ 300-31-20UG
This item is not returnable.
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Description
Recombinant Human Fractalkine is an 8.5 kDa protein containing 76 amino acid residues, including the four conserved cysteine residues present in CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.
Specifications
| P78423 | |
| protein with no preservative | |
| 8.5 kDa | |
| 20 μg | |
| RUO | |
| A-152E5.2; AB030188; ABCD-3; Acc1; AI848747; C3Xkine; chemokine (C-X3-C motif) ligand 1; CX3C; CX3C membrane-anchored chemokine; C-X3-C motif chemokine 1; C-X3-C motif chemokine ligand 1; Cx3cl1; CXC3; CXC3C; D8Bwg0439e; Fkn; Fractalkine; neurotactin; NTN; NTT; Processed fractalkine; SCYD1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D, 1; small-inducible cytokine D1 | |
| Cx3cl1 | |
| Unconjugated | |
| QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG | |
| E. coli | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| ELISA, Functional Assay, Western Blot | |
| 6376 | |
| Human Fractalkine (CX3CL1) | |
| E. coli | |
| <1 EU/ μg | |
| CX3CL1 | |
| Determined by its ability to chemoattract human T cells using a concentration range of 5.0-10.0 ng/ml | |
| Recombinant | |
| -20°C | |
| Lyophilized |
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Product Title
Gibco™ Human Fractalkine (CX3CL1) Recombinant Protein, PeproTech® > 20 μg; Unlabeled
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