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Cytiva HiTrap™ Capto™ MMC ImpRes Column
Prepacked with a weak cation exchange multimodal resin for screening and small-scale purifications
Brand: Cytiva 29401108
This item is not returnable.
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Description
- The multimodal functionality of Capto MMC ImpRes offers a different selectivity compared to traditional ion exchange columns
- Binds proteins at high or low ionic strength
- Efficiently removes contaminants such as DNA, host cell proteins (HCP), leached protein A, and aggregates
- An excellent choice for purification of MAbs and other biomolecules with high aggregate content.
- Can typically be used in the initial polishing step in MAb purification processes, as well as for polishing of antibody fragments such as domain antibodies (DAbs)
- High yields achieved through the high-resolution beads and selectivity of the ligand
- Enables use of a platform approach to MAb process development
- Displays a broad pH/salt operational window
- Ideal for screening of selectivity, binding, and elution conditions, as well as for small scale purifications
Specifications
| High-Resolution Polishing of Monoclonal Antibodies (MAbs) and Other Biomolecules | |
| <4 mL/min | |
| Multimodal Weak Cation Exchanger | |
| 60 to 90 mg MAb/mL | |
| Pre-packed Column | |
| 1 mL | |
| 1 Ea. |
| High-Flow Agarose | |
| Multimodal Ion Exchange Chromatography | |
| Store at 4°C to 30°C in 20% Ethanol, 0.2 M Sodium Acetate | |
| 5 bar (70 psi) | |
| 7 mm | |
| 3 to 12 | |
| 25 mm |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- HiTrap Capto MMC ImpRes, 1 x 1 ml
Signal Word
- Warning
Hazard Category
- Flammable liquid Category 3
Hazard Statement
- H226-Flammable liquid and vapour.
Precautionary Statement
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Supplemental information
- MIXTURE LIST-Contains : ethanol
- UNKNOWN ACUTE-16.5 per cent of the mixture consists of component(s) of unknown acute toxicity.