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endo-IWR 1, Tocris Bioscience™

Product Code. 18034102
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Wnt/β-catenin signaling inhibitor; axin stabilizer

endo-IWR 1 is an inhibitor of Wnt signaling. Induces an increase in axin2 protein levels; promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes. Promotes endothelial cell specification of cardiac progenitor cells

Negative Control also available.

For more information about how endo-IWR 1 may be used, see our protocol: Generation and Propagation of EPS cells (LCDM Cocktail) .

Chemical Identifiers

CAS 1127442-82-3
Molecular Formula C25H19N3O3
Molecular Weight (g/mol) 409.445
InChI Key ZGSXEXBYLJIOGF-HRQSHJORSA-N
Synonym iwr-1-endo, iwr-1
PubChem CID 91885421
SMILES C1C2C=CC1C3C2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6

Specifications

Quantity 50 mg
Formula Weight 409.44
Percent Purity >98%
Chemical Name or Material endo-IWR 1
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