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Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format
Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.
Brand: Thermo Scientific™ 21658
This item is not returnable.
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Description
Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.
Highlights:
- Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
- “Fix” protein interactions to allow identification of weak or transient protein interactions
- Protein crosslinking to create bioconjugates via single-step reactions
- Crosslink oriented antibodies to Protein A or G agarose
- Immobilize proteins onto amine-coated surfaces
Specifications
Amine-to-Amine | |
Pierce DSS | |
Yes | |
No | |
11.4Å | |
Not soluble in water |
No | |
Disuccinimidyl suberate; powder solid | |
368.34 | |
43mL of typical 1X (1mM) reaction solution (total), or 8 separate uses | |
8 x 2 mg |
For Research Use Only. Not for use in diagnostic procedures.