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Dansyl chloride, 96%, Thermo Scientific Chemicals

Product Code. 11424924
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Quantity:
1 g
5 g
25 g

Dansyl chloride is a fluorogenic reagent used for protein, N-terminal amino acid and peptide detection by reverse phase high performance liquid chromatography (HPLC). It is also used to determine the degree of labeling in chymotrypsin and ovalbumin. It acts as a precursor for the synthesis of other derivatives like dansyl amide.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Dansyl chloride is a fluorogenic reagent used for protein, N-terminal amino acid and peptide detection by reverse phase high performance liquid chromatography (HPLC). It is also used to determine the degree of labeling in chymotrypsin and ovalbumin. It acts as a precursor for the synthesis of other derivatives like dansyl amide.

Solubility
Soluble in dimethyl fluoride, acetone, chloroform, pyridine, benzene and dioxane. Insoluble in water.

Notes
Store in cool place. Moisture sensitive. Incompatible with strong bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 605-65-2
Molecular Formula C12H12ClNO2S
Molecular Weight (g/mol) 269.74
MDL Number MFCD00003985
InChI Key XPDXVDYUQZHFPV-UHFFFAOYSA-N
Synonym dansyl chloride, 5-dimethylamino naphthalene-1-sulfonyl chloride, dns chloride, dansyl, 5-dimethylamino-1-naphthalenesulfonyl chloride, 1-naphthalenesulfonyl chloride, 5-dimethylamino, 1-dimethylaminonaphthalene-5-sulfonyl chloride, 1-chlorosulfonyl-5-dimethylaminonaphthalene, unii-qmu9166tj4, 5-dimethylaminonaphthalene-1-sulphonyl chloride
PubChem CID 11801
ChEBI CHEBI:51907
IUPAC Name 5-(dimethylamino)naphthalene-1-sulfonyl chloride
SMILES CN(C)C1=CC=CC2=C(C=CC=C12)S(Cl)(=O)=O

Specifications

Melting Point 69°C to 75°C
Odor Odorless
Quantity 1 g
UN Number UN3261
Beilstein 2217205
Sensitivity Moisture sensitive
Merck Index 14,2814
Solubility Information Soluble in dimethyl fluoride,acetone,chloroform,pyridine,benzene and dioxane. Insoluble in water.
Formula Weight 269.75
Percent Purity 96%
Chemical Name or Material Dansyl chloride
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Product Identifier
  • Dansyl chloride
Signal Word
  • Danger
Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 1
  • Skin corrosion/irritation Category 1 B
Hazard Statement
  • H302-Harmful if swallowed.
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • EUH029-Contact with water liberates toxic gas.
Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
  • P402+P404-Store in a dry place. Store in a closed container.
Supplemental information
  • MIXTURE LIST-Contains : 5-(dimethylamino)-1-naphthalenesulfonylchloride

RUO – Research Use Only

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