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Cycloheximide, Tocris Bioscience™

Product Code. 30001156
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Quantity:
100 mg
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Description

Inhibitor of protein synthesis

Selective inhibitor of eukaryotic (over prokaryotic) protein synthesis, blocking tRNA binding and release from ribosomes. Induces apoptosis in a variety of transformed and normal cell lines, including T cells. Competitively inhibits the PPIase hFKBP12 (Ki = 3.4 μM). Also inhibits ferroptosis. Antifungal antibiotic. Exhibits anti-MERS-CoV activity in Vero cells in vitro (IC50 = 0.16 μM).

Specifications

CAS 66-81-9
Molecular Formula C15H23NO4
MDL Number MFCD00082346
Quantity 100 mg
Synonym cycloheximide, actidione, cycloheximide, naramycin a, kaken, actidion, actidone, hizarocin, naramycin, neocycloheximide
InChI Key YPHMISFOHDHNIV-QTEFRXOUNA-N
SMILES [H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1
IUPAC Name 4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
Molecular Weight (g/mol) 281.35
PubChem CID 6197
ChEBI CHEBI:27641
Formula Weight 281.35
Percent Purity >97%
Chemical Name or Material Cycloheximide
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