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Tocris Bioscience™ Bosentan

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

116.00€ - 407.00€

Specifications

Product Type Antagonist
Target Proteins Non-selective Endothelin Receptor
CAS 147536-97-8
Molecular Formula C27H29N5O6S
Formula Weight 551.61g/mol
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18758606
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Tocris Bioscience™
6232/10
10 mg
116.00€
10mg
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18706158
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Tocris Bioscience™
6232/50
50 mg
407.00€
50mg
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Description

Description

High affinity dual ETA and ETB receptor antagonist (Ki values are 4.7 and 95 nM for ETA and ETB, respectively). Inhibits ET-1 induced contraction of isolated rat aorta and sarafotoxin S6C-induced contraction of rat trachea in vitro. Orally bioavailable.
Specifications

Specifications

Antagonist
147536-97-8
551.61g/mol
Non-selective Endothelin Receptor Antagonists
Non-selective Endothelin Receptor
C27H29N5O6S
Store at 4°C
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