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Tocris Bioscience™ Bosentan

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

Brand: Tocris Bioscience™ 6232/10

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Product Code. 18758606

116.00€ / 10mg

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Description

Bosentan is a high affinity dual ETA and ETB receptor antagonist (Ki values are 4.7 and 95 nM for ETA and ETB, respectively). Inhibits ET-1 induced contraction of isolated rat aorta and sarafotoxin S6C -induced contraction of rat trachea in vitro. Orally bioavailable.

Specifications

Product Type	Antagonist
CAS	147536-97-8
Formula Weight	551.61g/mol
For Use With (Application)	Non-selective Endothelin Receptor Antagonists

Target Proteins	Non-selective Endothelin Receptor
Molecular Formula	C₂₇H₂₉N₅O₆S
Content And Storage	Store at 4°C
Quantity	10 mg

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Tocris Bioscience™ Bosentan

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