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Invitrogen™ BacMam LRRK2 Reagent

BacMam LRRK2 Reagent

Brand:  Invitrogen™ A13388

Product Code. 11350802

  • 2265.00€ / Each
Estimated Shipment: 16-01-2025
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Description

Description

BacMam LRRK2 Wild Type Reagent is a modified insect cell virus (baculovirus) that enables easy, efficient, and titratable overexpression of full-length wild-type LRRK2 in your choice of cellular background, including primary neurons and neuroblastoma cell lines.

BacMam LRRK2 Wild Type Reagent Lets You:

  • Easily overexpress full-length LRRK2 in most cellular backgrounds
  • Conduct the LRRK2 cellular assays you need
  • Understand the effects of therapeutically relevant LRRK2 mutations

    Examine LRRK2 Mutations with BacMam Reagents
    Use therapeutic mutant reagents G2019S (Cat. no. A13389) and D1994A (Cat. no. A13390) along with the wild-type LRRK2 reagent to enable your research into LRRK2 mutations, including exploration of differences in cellular response to stimulus among different mutations.

    Expand Your Battery of Cellular Assays for LRRK2
    Once full length LRRK2 has been introduced into your cellular background, the transduced cells allow you the flexibility to conduct many types of LRRK2 experiments, including studies of regulation of physiologically functional pathways (including signaling pathways leading to function), and identification of potential physiological substrates for LRRK2.

    Overexpress Full-Length LRRK2 in Most Mammalian Cell Backgrounds
    BacMam technology utilizes a modified baculovirus to deliver and express genes in mammalian cells with minimal effort and toxicity. It enables efficient, titratable LRRK2 protein expression in various mammalian cellular backgrounds, including cell lines that may not be compatible with traditional transfection methods, such as primary neurons and neuroblastoma cell lines.

    For research use only. Not intended for any human or animal therapeutic or diagnostic use.

    Related Links:
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  • Learn More About BacMam Technology
    TRUSTED_SUSTAINABILITY
    • Specifications

    Specifications

    Recombinant baculovirus particles suspended in Gibco™ Sf-900™ III SFM media supplemented with 3% heat-inactivated fetal bovine serum (hiFBS)
    Kinases
    15 mL
    LRRK2
    Wet Ice
    BacMam LRRK2 Reagent
    Baculovirus (BacMam System)
    Recombinant baculovirus particles suspended in Gibco™ Sf-900™ III SFM media (Cat# 12658) supplemented with 3% heat-inactivated fetal bovine serum (hiFBS) (Cat# 10100). Store at 4°C, keep sterile, protect from light, DO NOT freeze, aliquot upon arrival.
    Kinases
    Overexpression of full-length wild-type LRRK2
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    For Research Use Only. Not for use in diagnostic procedures.