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Aluminon, Thermo Scientific Chemicals Product Code.: 11478366
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Aluminon, Thermo Scientific Chemicals

Product Code. 11478366
250 g
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250 g
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Product Code. 11478366

Brand: Thermo Scientific Alfa Aesar A15401.30

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234.51 EUR valid until 2025-03-29
Use promo code "24111" to get your promotional price.

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This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”24111” to get your promotional price

Description

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types.

Solubility
Soluble in water(800g/L).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 569-58-4
Molecular Formula C22H23N3O9
Molecular Weight (g/mol) 473.438
MDL Number MFCD00040925
InChI Key AIPNSHNRCQOTRI-UHFFFAOYSA-N
Synonym Aurintricarboxylic acid triammonium salt
PubChem CID 54729869
ChEBI CHEBI:87398
IUPAC Name triazanium;5-[(3-carboxy-4-oxidophenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-oxidobenzoate
SMILES C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]

Specifications

Melting Point 220°C to 225°C (decomposition)
Merck Index 14,322
Solubility Information Soluble in water(800g/L).
Formula Weight 473.44
Odor Odorless
pH 5.3
Quantity 250 g
Chemical Name or Material Aluminon

RUO – Research Use Only

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