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Description
Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC50 values are 0.85 and 0.86 μM respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy).

Specifications
Specifications
CAS | 59277-89-3 |
Molecular Formula | C8H11N5O3 |
MDL Number | MFCD00057880 |
Quantity | 50 mg |
Synonym | acyclovir, aciclovir, acycloguanosine, zovirax, vipral, virorax, wellcome-248u, 9-2-hydroxyethoxy methyl guanine, zovir, aciclovirum |
InChI Key | MKUXAQIIEYXACX-UHFFFAOYSA-N |
SMILES | NC1=NC2=C(N=CN2COCCO)C(=O)N1 |
IUPAC Name | 2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-1H-purin-6-one |
Molecular Weight (g/mol) | 225.21 |
PubChem CID | 2022 |
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Acyclovir, Tocris Bioscience™ >
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