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Tocris Bioscience™ AC 5216

Selective TSPO ligand

Brand:  Tocris Bioscience™ 5281/10

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Product Code. 18756218

  • 243.00€ / 10mg

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Description

Description

AC 5216 is a ligand of translocator protein (TSPO, peripheral benzodiazepine receptor). Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.
Specifications

Specifications

>98%
AC 5216
AC 5216
10 mg
401.46
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