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Thermo Scientific Chemicals 5-Fluorouracil, 99% Product Code.: 11906531
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Thermo Scientific Chemicals 5-Fluorouracil, 99%

Product Code. 11906531
25 g, Glass bottle
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Quantity:
1 g
5 g
25 g
100 g
Packaging:
Glass bottle
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Product Code. 11906531

Brand: Thermo Scientific Chemicals 228440250

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Description

5-Fluorouracil, CAS # 51-21-8, is an analogue base composed of uracil with a position 5 hydrogen fluorine substitution.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• 5-Fluorouracil is an antimetabolite and antineoplastic that prevents DNA synthesis by blocking conversion of deoxyuridylic acid

• 5-Fluorouracil can replace uracil in RNA and prevent protein synthesis and cell growth

Applications

• 5-Fluorouracil can be used for laboratory research on tumor growth and immunosuppression

• 5-Fluorouracil may also be appropriate for laboratory studies of neurotoxicity, cell lysis, and DNA damage

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 51-21-8
Molecular Formula C4H3FN2O2
Molecular Weight (g/mol) 130.08
MDL Number MFCD00006018
InChI Key GHASVSINZRGABV-UHFFFAOYSA-N
Synonym 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton
PubChem CID 3385
ChEBI CHEBI:46345
IUPAC Name 5-fluoro-1H-pyrimidine-2,4-dione
SMILES FC1=CNC(=O)NC1=O

Specifications

Melting Point 278.0°C to 282.0°C
Color White
Boiling Point 190.0°C to 200.0°C (0.1 mmHg)
Loss on Drying 0.5% (80°C, 4 hrs) (in vacuum) max.
Infrared Spectrum Authentic
Assay Percent Range 99%
Packaging Glass bottle
Quantity 25 g
Beilstein 24,IV,1229
Merck Index 15,4213
Solubility Information Solubility in water: 12.2g/L (20°C). Other solubilities: 2.9g/L (20°C) in ethanol,readily soluble in aqueous alkali solutions,soluble in dmso
Formula Weight 130.08
Percent Purity 99%
Physical Form Crystalline Powder
Chemical Name or Material 5-Fluorouracil
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Certificates

Certificates

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3 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberAB404993 Certificate TypeCertificate of Analysis Date18/02/2025 Catalog Number
Lot NumberA0450008 Certificate TypeCertificate of Analysis Date02/05/2023 Catalog Number228440250,228440010,228440050
Lot NumberA0305173 Certificate TypeCertificate of Analysis Date22/03/2021 Catalog Number

Safety and Handling

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Product Identifier
  • 5-Fluorouracil
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 3
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Germ cell mutagenicity Category 2
  • Reproductive toxicity Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H341-Suspected of causing genetic defects.
  • H361d-Suspected of damaging the unborn child.
  • H335-May cause respiratory irritation.
  • H312-Harmful in contact with skin.
  • H332-Harmful if inhaled.
  • H301-Toxic if swallowed.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
SDS

RUO – Research Use Only

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