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  5. Thermo Scientific Chemicals 3,4-Dihydroxy-L-phenylalanine, 98+%

Thermo Scientific Chemicals 3,4-Dihydroxy-L-phenylalanine, 98+%

Product Code. 11443704
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Quantity:
5 g
25 g
100 g

Description

3-(3,4-Dihydroxyphenyl)-L-alanine (levodopa orL-dopa), CAS # 59-92-7, is a dopamine precursor molecule.

3,4-dihydroxy-L-phenylalanine (DOPA) is used as a cell adhesion molecule in serum-free cultures of anchorage-dependent mammalian cells. It is also used as an anticholinergic drug and used in the treatment of Parkinson's disease. It acts as an intermediate in the biosynthesis of other catecholamines (norepinephrine, epinephrine) and melanin. It acts as a precursor of dopamine product of tyrosine hydroxylase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• 3-(3,4-Dihydroxyphenyl)-L-alanine, or L-dopa, is converted to dopamine by DOPA decarboxylase in the body
• Upon conversion to dopamine, it acts as an excitatory neurotransmitter
Applications
• L-dopa is useful in the laboratory study of Parkinson’s to replenish dopamine in depleted circuits
• L-dopa has also been used for laboratory research on hypertension and melanocyte activity
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 59-92-7
Molecular Formula C9H11NO4
Molecular Weight (g/mol) 197.19
MDL Number MFCD00002598
InChI Key WTDRDQBEARUVNC-LURJTMIESA-N
Synonym levodopa, l-dopa, dopar, 3-hydroxy-l-tyrosine, 3,4-dihydroxy-l-phenylalanine, larodopa, bendopa, levopa, dihydroxy-l-phenylalanine, cidandopa
PubChem CID 6047
ChEBI CHEBI:15765
IUPAC Name (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
SMILES N[C@@H](CC1=CC=C(O)C(O)=C1)C(O)=O

Specifications

Melting Point ∼295°C (decomposition)
Beilstein 2215169
Merck Index 14,5464
Solubility Information Slightly soluble in water,dilute hydrochloric acid and formic acid. Insoluble in ethanol.
Quantity 5 g
Odor Odorless
Formula Weight 197.19
Sensitivity Light sensitive
Percent Purity ≥98%
Chemical Name or Material 3,4-Dihydroxy-L-phenylalanine

Safety and Handling

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Product Identifier
  • 3,4-Dihydroxy-L-phenylalanine
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
 Hazard Statement
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : 3,4-Dihydroxy-L-phenylalanine

RUO – Research Use Only

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