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Thermo Scientific™ TheraPure™ 2'-OMe-Bz-A Phosphoramidite, 20-400 finish bottle

2'-OMe-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-2042-10

Product Code. 17987112

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Description

Description

2'-OMe-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-O-methyl-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C48H54N7O8P
• Base: A
• Base Protection: Bz
• Formula weight: 887.97 g/mol
• CAS number: 110782-31-5
• HPLC purity: ≥99%; M-11 Impurity: ≤0.01%; Single critical impurity ≤0.3%
• 31P NMR purity: >99%; Sum of non-primary peaks at 140-152 ppm ≤0.5%

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Expedite Synthesizers
Store in freezer (at or below -20°C).
2in-OMe modified
99%
Phosphoramidite
RNA
Powder
2in-OMe-Bz-A CEP
Adenosine (A)
Room Temperature
1 g
TheraPure™
TheraPure™
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Thermo Scientific™ TheraPure™ 2'-OMe-Bz-A Phosphoramidite, 20-400 finish bottle > 1 g

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