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Thermo Scientific™ 2'-Fluoro-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle

2'-Fluoro-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-Fluoro protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-1601-09

Product Code. 17964272

  • 34.10€ / 250mg

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Description

Description

2'-Fluoro-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

≥98%
Expedite Synthesizers
875.92 g/mol
Store in freezer (at or below -20°C).
2in-Fluoro modified
>98% (HPLC)
Phosphoramidite
RNA
Powder
C47H51FN7O7P
Amber bottle (20-400 finish neck style)
Base: A
Base Protection: Bz
2in-Fluoro-Bz-A CEP
Adenosine (A)
Room Temperature
0.25 g
Standard
Oligonucleotide synthesis
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
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Lot Number Certificate Type Date Catalog Number
Lot NumberYB0622 Certificate TypeCertificate of Analysis Date29/01/2025 Catalog Number27-1601-09
Lot NumberYK2592 Certificate TypeCertificate of Analysis Date28/01/2025 Catalog Number27-1601-09
Lot NumberYL1282 Certificate TypeCertificate of Analysis Date28/01/2025 Catalog Number27-1601-09
Lot NumberZA3562 Certificate TypeCertificate of Analysis Date28/01/2025 Catalog Number27-1601-09
Lot NumberZD1452 Certificate TypeCertificate of Analysis Date26/01/2025 Catalog Number27-1601-09
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Thermo Scientific™ 2'-Fluoro-Bz-A Phosphoramidite, standard grade, 20-400 finish bottle > 0.25 g

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