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  5. Tocris Bioscience™ XL 184

Tocris Bioscience™ XL 184
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Product Code. 18716229
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 18716229

Brand: Tocris Bioscience™ 5422/10

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This item is not returnable. View return policy

Description

Potent VEGFR inhibitor; also inhibits other RTKs

XL 184 is a potent VEGFR inhibitor (IC50 = 0.035 nM); also inhibits c-Met, KIT, RET, FLT4, AXL, FLT3, FLT1 and Tie2 (IC50 values are 1.3, 4.6, 5.2, 6, 7, 11.3, 12 and 14.3 nM, respectively). Induces intratumoral hypoxia and apoptosis. Reduces tumor invasion and metastasis in vivo. Antiangiogenic.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type XL 184
Purity >98%
Molecular Weight (g/mol) 501.51
Inhibitors XL 184

For Research Use Only

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