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(-)-Xestospongin C, Tocris Bioscience™

Product Code. 18076042
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Quantity:
10 μg
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Description

Reported inhibitor of IP3-dependent Ca2+ release

Reported inhibitor of IP3-dependent Ca2+ release. Inhibits bradykinin -induced Ca2+ release in PC12 cells and attenuates PHP-induced IL-2 production in Jurkat T cells. Exhibits no effect on ryanodine receptor-mediated Ca2+ release in PC12 cells. Does not interact with the IP3 binding site. Recently shown to be an ineffective antagonist of IP3-evoked Ca2+ release in IP3 receptor expressing DT40 cells. Cell permeable.

Specifications

CAS 88903-69-9
Molecular Formula C28H50N2O2
Quantity 10 μg
Synonym (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine
InChI Key PQYOPBRFUUEHRC-FRZROCRGSA-N
SMILES C1CCCC2CCN3CCCC(C3O2)CCCCCCC4CCN5CCCC(C5O4)CC1
Molecular Weight (g/mol) 446.72
PubChem CID 51026240
Formula Weight 446.71
Percent Purity >98%
Chemical Name or Material (-)-Xestospongin C
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