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  8. VER 155008, Tocris Bioscience™

VER 155008, Tocris Bioscience™

Product Code. 18094762
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Hsp70 inhibitor

Novel adenosine-derived inhibitor of Heat Shock Protein 70 (Hsp70) (IC50 = 0.5 μM). Inhibits cell proliferation of multiple human tumor cell lines in vitro. Also binds Hsc70 and Grp78; displays selectivity against Hsp90β (IC50 >200 μM for Hsp90β).

Chemical Identifiers

CAS 1134156-31-2
Molecular Formula C25H23Cl2N7O4
Molecular Weight (g/mol) 556.40
MDL Number MFCD18086892
InChI Key ZXGGCBQORXDVTE-UHFFFAOYNA-N
Synonym 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl methyl amino-adenosine, 5'-o-4-cyanophenyl methyl-8-3,4-dichlorophenyl-methyl amino-adenosine, 4-2r,3s,4r,5r-5-6-amino-8-3,4-dichlorobenzyl amino-9h-purin-9-yl-3,4-dihydroxytetrahydrofuran-2-yl methoxy methyl benzonitrile, 3fd, d0h0au, adenosine-derived inhibitor, 12, hsp 70 inhibitor cancer , vernalis, adenosine-derived inhibitor grp78 , 13, ver hplc, heat shock protein 70 inhibitor cancer , vernalis
PubChem CID 25195348
IUPAC Name 4-({[5-(6-amino-8-{[(3,4-dichlorophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}methyl)benzonitrile
SMILES NC1=C2N=C(NCC3=CC(Cl)=C(Cl)C=C3)N(C3OC(COCC4=CC=C(C=C4)C#N)C(O)C3O)C2=NC=N1

Specifications

Quantity 50 mg
Formula Weight 556.4
Percent Purity >98%
Chemical Name or Material VER 155008
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