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  6. 30001377

U 46619, Tocris Bioscience™

Product Code. 30001377
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Quantity:
1 mg
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Description

Potent, stable thromboxane A2 (TP) receptor agonist

PGH2 (TXA2) analog that is a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0.035 μM). Potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations. Activates ERK-1 and ERK-2 in HEK 293 cells expressing TPα and TPβ receptors.

Specifications

CAS 56985-40-1
Molecular Formula C21H34O4
Quantity 1 mg
Synonym (5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid
InChI Key LQANGKSBLPMBTJ-QQBDIJMNSA-N
SMILES CCCCCC(C=CC1C2CC(C1CC=CCCCC(=O)O)CO2)O
IUPAC Name (E)-7-[(1R,2S,3R,4R)-3-[(Z,3S)-3-hydroxyoct-1-enyl]-5-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid
Molecular Weight (g/mol) 350.499
PubChem CID 122173090
Formula Weight 350.5
Percent Purity >98%
Chemical Name or Material U 46619
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