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TRAM 34, Tocris Bioscience™

Product Code. 30002117
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and highly selective KCa3.1 channel blocker

Potent and highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.

Chemical Identifiers

CAS 289905-88-0
Molecular Formula C22H17ClN2
Molecular Weight (g/mol) 344.842
InChI Key KBFUQFVFYYBHBT-UHFFFAOYSA-N
Synonym tram-34, 1-2-chlorophenyl diphenylmethyl-1h-pyrazole, tram 34, 1-2-chlorophenyl-diphenylmethyl pyrazole, surecn41130, d03yvq, d05rlr, tram hplc , solid, 1-2-chlorophenyl-diphenyl-methyl pyrazole
PubChem CID 656734
ChEBI CHEBI:34990
IUPAC Name 1-[(2-chlorophenyl)-diphenylmethyl]pyrazole
SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CC=N4

Specifications

Quantity 10 mg
Formula Weight 344.84
Percent Purity >99%
Chemical Name or Material TRAM 34
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