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TC-S 7005, Tocris Bioscience™
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Quantity:
10 mg
Description
Potent and selective polo-like kinase 2 (PLK2) inhibitor (IC50 = 4 nM). Shows selectivity for PLK2 over PLK3 and PLK1 (IC50 values are 24 and 214 nM respectively). Induces mitotic arrest and cell death in HCT 116 colorectal cells.
Specifications
Specifications
CAS | 1082739-92-1 |
Color | Cream |
Molecular Formula | C21H17N3O3 |
Quantity | 10 mg |
Synonym | 2-amino-isoxazolopyridine, 9, 3-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl-isoxazolo 5,4-c pyridin-5-amine, 3-2h-1,3-benzodioxol-5-yl-n-1s-1-phenylethyl pyrido 4,3-d 1,2 oxazol-5-amine |
InChI Key | DAAGOCSHXCDWDY-ZDUSSCGKSA-N |
SMILES | CC(C1=CC=CC=C1)NC2=NC=C3C(=C2)C(=NO3)C4=CC5=C(C=C4)OCO5 |
IUPAC Name | 3-(1,3-benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]-[1,2]oxazolo[5,4-c]pyridin-5-amine |
Molecular Weight (g/mol) | 359.385 |
PubChem CID | 24971422 |
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