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  7. T16Ainh - A01, Tocris Bioscience™

T16Ainh - A01, Tocris Bioscience™

Product Code. 18025212
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Quantity:
10 mg
50 mg
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Description

Ca2+-activated Cl- channel transmembrane protein 16A (TMEM16A) inhibitor

Inhibitor of Ca2+-dependent Cl- channel (CaCC) transmembrane protein 16A (TMEM16A) (IC50 = 1.8 μM in A253 salivary gland epithelial cells). Inhibits EGF-induced increases in CaCC currents; blocks proliferation of tumor cells in vitro.

Chemical Identifiers

CAS 552309-42-9
Molecular Formula C19H20N4O3S2
Molecular Weight (g/mol) 416.514
InChI Key QSIYTNYMBWYHAA-UHFFFAOYSA-N
Synonym t16a inh-a01, t16ainh-a01, 2-5-ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl thio-n-4-4-methoxyphenyl thiazol-2-yl acetamide, 2-5-ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl thio-n-4-4-methoxyphenyl-2-thiazolyl acetamide, 2-5-ethyl-4-hydroxy-6-methylpyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, t16ainh-a hplc, 2-5-ethyl-4-hydroxy-6-methylpyrimidin-2-ylthio-n-4-4-methoxyphenyl thiazol-2-yl acetamide, 2-5-ethyl-4-methyl-6-oxo-3h-pyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, 2-5-ethyl-6-methyl-4-oxo-1h-pyrimidin-2-yl sulfanyl-n-4-4-methoxyphenyl-1,3-thiazol-2-yl acetamide, n-4-4-methoxyphenyl thiazole-2-yl-2-4-hydroxy-5-ethyl-6-methylpyrimidine-2-ylthio acetamide
PubChem CID 3193184
IUPAC Name 2-[(5-ethyl-6-methyl-4-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]acetamide
SMILES CCC1=C(NC(=NC1=O)SCC(=O)NC2=NC(=CS2)C3=CC=C(C=C3)OC)C

Specifications

Quantity 50 mg
Formula Weight 416.52
Percent Purity >98%
Chemical Name or Material T16Ainh - A01
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