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SCH 442416, Tocris Bioscience™

Product Code. 18054922
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1 mg
10 mg
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Description

Very selective, high affinity A2A antagonist

Selective adenosine A2A receptor antagonist; binds to human and rat A2A receptors with high affinity (Ki values are 0.048 and 0.5 nM respectively). Displays > 23000-fold selectivity for hA2A over hA1 in vitro with minimal affinity for hA2B and hA3 receptors (IC50 > 10 μM). Blocks the cytoprotective effect of A2A agonist CGS-21680 (Cat.No. 1063).

Chemical Identifiers

CAS 316173-57-6
Molecular Formula C20H19N7O2
Molecular Weight (g/mol) 389.419
InChI Key AEULVFLPCJOBCE-UHFFFAOYSA-N
Synonym unii-zmc4g1w59s, 2-furan-2-yl-7-3-4-methoxyphenyl propyl-7h-pyrazolo 4,3-e 1,2,4 triazolo 1,5-c pyrimidin-5-amine, zmc4g1w59s, 4-furan-2-yl-10-3-4-methoxyphenyl propyl-3,5,6,8,10,11-hexaazatricyclo 7.3.0.0 2 ,? dodeca-1 9 ,2,4,7,11-pentaen-7-amine, d02yqo, 2-2-furanyl-7-3-4-methoxyphenyl propyl-7h-pyrazolo 4,3-e 1,2,4 triazolo 1,5-c pyrimidin-5-amine, sch hplc, 2-2-furanyl-7-3-4-methoxyphenyl propyl-7h-pyrazolo 4,3-e 1,2,4 triazolo 1,5-c pyrimidin-5-amine; 5-amino-7-3-4-methoxyphenyl propyl-2-2 furyl pyrazolo 4,3-e-1,2,4-triazolo 1,5-c pyrimidine, 2-2-furanyl-7-3-4-methoxyphenyl propyl-7h-pyrazolo 4,3-e 1,2,4 triazolo 1,5-c pyrimidin-5-amine; 5-amino-7-3-4-methoxyphenyl propyl-2-2 furyl pyrazolo 4,3-e-1,2,4-triazolo 1,5-c pyrimidine; 5-amino-7-3-4-methoxy phenylpropyl-2-2-furyl-pyrazolo 4,3-e-1,2,4, 2-furan-2-yl-7-3-4-methoxyphenyl propyl-7h-pyrazolo-4,3-e 1,2,4 triazolo 1,5-c pyrimidin-5-amine
PubChem CID 10668061
SMILES COC1=CC=C(C=C1)CCCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5

Specifications

Quantity 1 mg
Formula Weight 389.42
Percent Purity >99%
Chemical Name or Material SCH 442416
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