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  8. 18074372

SC 560, Tocris Bioscience™

Product Code. 18074372
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Quantity:
10 mg
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Description

Cyclooxygenase-1 (COX-1) inhibitor

Highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.009 and 6.3 μM for COX-1 and COX-2 respectively). Inhibits COX-1-derived platelet thromboxane B2, gastric PGE2 and dermal PDE2 production. Significantly reduces ovarian surface epithelial tumor growth in vivo. Orally active.

Specifications

CAS 188817-13-2
Molecular Formula C17H12ClF3N2O
MDL Number MFCD02179214
Quantity 10 mg
Synonym 5-4-chlorophenyl-1-4-methoxyphenyl-3-trifluoromethyl-1h-pyrazole, razole, 5-4-chlorophenyl-1-4-methoxyphenyl-3-trifluoromethylpyrazole, chembl26915, 5-4-chlorophenyl-1-4-methoxyphenyl-3-trifluoromethyl pyrazole, lopac-s-2064, d0m5mi, sc hplc, 5-4-chlorophenyl-1-4-methoxyphenyl-3-trifluoromethyl-1h-py
InChI Key PQUGCKBLVKJMNT-UHFFFAOYSA-N
SMILES COC1=CC=C(C=C1)N1N=C(C=C1C1=CC=C(Cl)C=C1)C(F)(F)F
IUPAC Name 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole
Molecular Weight (g/mol) 352.74
PubChem CID 4306515
ChEBI CHEBI:76274
Formula Weight 352.74
Percent Purity >98%
Chemical Name or Material SC 560
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