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R&D Systems™ Mca-SEVNLDAEFRK(Dnp)RR-NH2 Fluorogenic Peptide Substrate
Applications: Bioactivity
Brand: R&D Systems™ ES004
This item is not returnable.
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Description
- Contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2, 4-dinitrophenyl group
- It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence
- Purity 93.8% by HPLC
- Contains the Swedish mutation of the amyloid precursor protein (APP) beta-secretase cleavage site
- A K-R-R sequence is added for easy solubilization
Specifications
| Liquid | |
| Supplied as a stock solution in dimethyl sulfoxide (DMSO) (100μL) at a concentration of 10.0mg/mL or 4.1 mM.. | |
| Source: Synthetic |
| Bioactivity | |
| Predicted MW: 2001 Da | |
| Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light |
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