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  7. Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine, Thermo Scientific Chemicals

Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine, Thermo Scientific Chemicals

Product Code. 11488683
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Quantity:
10 g
50 g
250 g
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Description

Quinine is used in photochemistry as a common fluorescence standard and as a resolving agent for chiral acids. It is also useful for treating falciparum malaria, lupus, arthritis and vivax malaria. It acts as a flavor component in tonic water and bitter lemon. It is utilized as the chiral moiety for the ligands used in sharpless asymmetric dihydroxylation. Furthermore, it catalyzes the kinetic resolution of furanones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Quinine is used in photochemistry as a common fluorescence standard and as a resolving agent for chiral acids. It is also useful for treating falciparum malaria, lupus, arthritis and vivax malaria. It acts as a flavor component in tonic water and bitter lemon. It is utilized as the chiral moiety for the ligands used in sharpless asymmetric dihydroxylation. Furthermore, it catalyzes the kinetic resolution of furanones.

Solubility
Soluble in alcohol, chloroform and diethyl ether. Slightly soluble in water and glycerol.

Notes
Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 130-95-0
Molecular Formula C20H24N2O2
Molecular Weight (g/mol) 324.42
MDL Number MFCD00198096
InChI Key LOUPRKONTZGTKE-ZCXAXGJJNA-N
Synonym 1r-6-methoxyquinolin-4-yl 1s,4s,5r-5-vinylquinuclidin-2-yl methanol, quinine anhydrous, +-2,3-o-isopropylidene-l-threitol
PubChem CID 129316724
SMILES [H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C

Specifications

Melting Point ∼177°C (decomposition)
Quantity 50 g
Beilstein 91867
Sensitivity Light Sensitive
Merck Index 14,8061
Solubility Information Soluble in alcohol,chloroform and diethyl ether. Slightly soluble in water and glycerol.
Optical Rotation −166° (c=1 in ethanol)
IUPAC Name (5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-[6-(trideuteriomethoxy)quinolin-4-yl]methanol
Formula Weight 324.42
Percent Purity 99%
Assay (total base)
Chemical Name or Material Quinine, Anhydrous, may cont. up to 5% dihydroquinine
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Safety and Handling

compliance-icons
Product Identifier
  • Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Skin sensitiser Category 1
 Hazard Statement
  • H302-Harmful if swallowed.
  • H317-May cause an allergic skin reaction.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : Quinine

RUO – Research Use Only

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