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  8. QNZ 46, Tocris Bioscience™

QNZ 46, Tocris Bioscience™

Product Code. 30001653
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Quantity:
10 mg
50 mg
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Description

NR2C/NR2D-selective NMDA receptor non-competitive antagonist

GluN2C/GluN2D-selective NMDA receptor non-competitive antagonist (IC50 values are 3, 6, 229, and >300, >300 μM for GluN2D, GluN2C, GluN2A, GluN2B, and GluR1, respectively). Requires binding of glutamate to the GluN2 subunit.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Chemical Identifiers

CAS 1237744-13-6
Molecular Formula C24H17N3O6
Molecular Weight (g/mol) 443.415
InChI Key GNLVJIICVWDSNI-LFYBBSHMSA-N
Synonym qnz46, qnz 46, 4-6-methoxy-2-1e-2-3-nitrophenyl ethenyl-4-oxo-3 4h-quinazolinyl-benzoic acid, qnz hplc, e-4-6-methoxy-2-3-nitrostyryl-4-oxoquinazolin-3 4h-yl-benzoic acid, 4-6-methoxy-2-1e-2-3-nitrophenyl ethenyl-4-oxo-3 4h quinazolinyl benzoic acid, 4-6-methoxy-2-e-2-3-nitrophenyl ethenyl-4-oxoquinazolin-3-yl benzoic acid
PubChem CID 46861929
IUPAC Name 4-[6-methoxy-2-[(E)-2-(3-nitrophenyl)ethenyl]-4-oxoquinazolin-3-yl]benzoic acid
SMILES COC1=CC2=C(C=C1)N=C(N(C2=O)C3=CC=C(C=C3)C(=O)O)C=CC4=CC(=CC=C4)[N+](=O)[O-]

Specifications

Quantity 50 mg
Formula Weight 443.41
Percent Purity >98%
Chemical Name or Material QNZ 46
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