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Specifications
Chemical Name or Material | N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide |
---|---|
CAS | 1315323-00-2 |
Target | TRPC Channel Blockers |
Molecular Formula | C18H13F6N3O2S |
Purity | 0.98 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18758536
|
Tocris Bioscience™
6941/10 |
10 mg |
187.00€
10mg |
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18768946
|
Tocris Bioscience™
6941/50 |
50 mg |
682.00€
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Pyr 10 is a TRPC3 (transient receptor potential canonical 3) channel inhibitor (IC50 = 0.72 μM for TRPC3 mediated calcium entry in vitro), which displays approximately 18-fold selectivity for TRPC3-mediated receptor operated calcium entry (ROCE) over STIM1/Orai1-mediated store operated calcium entry (SOCE). Pyr 10 inhibits NFATc3 activation and inhibits proliferation of rat ventricular cardiac fibroblasts.Specifications
N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide | |
TRPC Channel Blockers | |
0.98 |
1315323-00-2 | |
C18H13F6N3O2S |
Safety and Handling
Recommended Storage : Store at -20°C