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Psora 4, Tocris Bioscience™

Product Code. 18075952
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent KV1.3 channel blocker

Potent KV1.3 channel blocker (EC50 = 3 nM). Preferentially binds the C-type inactivated state of the channel, similar to the activity of CP 339818 (Cat. No. 1399). Displays 17- to 70-fold selectivity over closely-related KV1 channels (KV1, KV2, KV4 and KV7); exhibits activity at KV1.5 (IC50 = 7.7 nM). Suppresses proliferation of human and rat myelin-specific effector memory T cells (EC50 values are 25 and 60 nM respectively).

Chemical Identifiers

CAS 724709-68-6
Molecular Formula C21H18O4
Molecular Weight (g/mol) 334.371
InChI Key JJAWGNIQEOFURP-UHFFFAOYSA-N
Synonym psora-4, psora 4, 5-4-phenylbutoxy psoralen, 4-4-phenylbutoxy furo 3,2-g chromen-7-one, 4-4-phenylbutoxy-7h-furo 3,2-g chromen-7-one, 4-4-phenylbutoxy-7h-furo 3,2-g 1 benzopyran-7-one, lopac-p-9872, d01nck, d0h1ei, psora hplc
PubChem CID 6603977
IUPAC Name 4-(4-phenylbutoxy)furo[3,2-g]chromen-7-one
SMILES C1=CC=C(C=C1)CCCCOC2=C3C=CC(=O)OC3=CC4=C2C=CO4

Specifications

Quantity 10 mg
Formula Weight 334.37
Percent Purity >99%
Chemical Name or Material Psora 4
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