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PROTEIN S Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA590849
This item is not returnable.
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Description
Immunogen sequence: MDINKPGPLF KPENGLLETK VYFAGFPRKV ESELIKPINP RLDGCIRSWN LMKQGASGIK EIIQEKQNKH CLVTVEKGSY YPGSGIAQFH IDYNNVSSAE GWHVNVTLNI RPSTGTGVML ALVSGNNTVP FAVSLVDSTS EKSQDILLSV ENTVIYRIQA LSLCSDQQSH LEFRVNRNNL ELSTPLKIET ISHEDLQRQL AVLDKAMKAK VATYLGGLPD VPFSATPVNA FYNGCMEVNI NGVQLDLDEA ISKHNDIRAH SCPSVWKKTK NS; Positive Samples: LO2, HeLa, 293T, Mouse liver, Mouse kidney, Rat liver, Rat kidney
Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 μg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
Specifications
| PROTEIN S | |
| Polyclonal | |
| Unconjugated | |
| PROS1 | |
| AW214361, Preproprotein S, PROS, PROS 1, PROS1, protein S, protein S (alpha), Protein S alpha, protein Sa, proteinS, PS 21, PS 22, PS 23, PS 24, PS 25, PS 26, PS21, PS22, PS23, PS24, PS25, PS26, PSA, rabbit protein S, THPH5, THPH6, unnamed protein product, vitamin K-dependent plasma protein S, vitamin K-dependent protein S, vitamin K-dependent protein S precursor | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 19128, 5627, 81750 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 3.65 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal, pH 7.3 | |
| P07225, P53813, Q08761 | |
| PROS1 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 405-676 of human PROS1 (NP_0003042) | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |