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PRIMA-1, Tocris Bioscience™

Catalog Number 18085132
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Quantity:
10 mg
50 mg
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5608-24-2
C9H15NO3
185.223
RFBVBRVVOPAAFS-UHFFFAOYSA-N
prima-1, 2,2-bis hydroxymethyl-1-azabicyclo 2,2,2, octan-3-one, 2,2-bis hydroxymethyl-1-azabicyclo 2.2.2 octan-3-one, 2,2-bis hydroxymethyl-3-quinuclidinone, p53 reactivation and induction of massive apoptosis, 2,2-bishydroxymethyl-1-aza-bicyclo 2.2.2 octan-3-one, 2,2-bis hydroxymethyl-1-azabicyclo 2,2,2 octan-3-one, prima 1, tocris-1862, prima 1;prima1
322968
2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one
C1CN2CCC1C(=O)C2(CO)CO
This item is not returnable. View return policy
5608-24-2
C9H15NO3
185.223
RFBVBRVVOPAAFS-UHFFFAOYSA-N
prima-1, 2,2-bis hydroxymethyl-1-azabicyclo 2,2,2, octan-3-one, 2,2-bis hydroxymethyl-1-azabicyclo 2.2.2 octan-3-one, 2,2-bis hydroxymethyl-3-quinuclidinone, p53 reactivation and induction of massive apoptosis, 2,2-bishydroxymethyl-1-aza-bicyclo 2.2.2 octan-3-one, 2,2-bis hydroxymethyl-1-azabicyclo 2,2,2 octan-3-one, prima 1, tocris-1862, prima 1;prima1
322968
2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one
C1CN2CCC1C(=O)C2(CO)CO

Description

Restores mutant p53 activity; induces apoptosis

Selectively restores mutant p53 activity in tumor cells via activation of Bax and PUMA. Induces apoptosis and inhibits growth of tumors with mutant p53.
Quantity 10 mg
Formula Weight 185.22
Percent Purity >99%
Chemical Name or Material PRIMA-1
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