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Thermo Scientific™ PMPI (p-maleimidophenyl isocyanate)

Short (8.7A) hydroxyl-to-sulfhydryl crosslinker; isocyanate and maleimide groups; label -OH by urethane bonds for conjugation to cysteines by thioether bonds.

Brand:  Thermo Scientific™ 28100

Product Code. 11831445

  • 239.00€ / 50mg
Estimated Shipment: 02-12-2024
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Description

Description

Thermo Scientific™ Pierce PMPI is a maleimide-and-isocyanate crosslinker for attaching compounds to sulfhydryl groups (cysteines) after conjugating the linker to hydroxyl groups on a molecule by urethane (carbamate) bonds.

Highlights:

  • Maleimide forms stable thioether linkages
  • Isocyanate reacts with - OH groups to form a carbamate link at pH 8.5
  • Excellent tool for conjugating - OH group-containing compounds such as steroids and vitamins
  • Reactive groups: maleimide and isocyanate
  • Reactive toward: sulfhydryl and hydroxyl groups
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Carboxyl-Sulfhydryl
PMPI
No
Upon receipt store at 4°C protected from moisture.
Ambient
Chemical Labeling
Maleimide, Isocyanate
Solid
DMF, DMSO
No
No
307.1
8.7 Å
Not determined
Pierce™
Heterobifunctional
Short (<10 Å)
50 mg
Standard
Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.