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Thermo Scientific™ PMPI (p-maleimidophenyl isocyanate)
Short (8.7A) hydroxyl-to-sulfhydryl crosslinker; isocyanate and maleimide groups; label -OH by urethane bonds for conjugation to cysteines by thioether bonds.
Brand: Thermo Scientific™ 28100
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Description
Thermo Scientific™ Pierce PMPI is a maleimide-and-isocyanate crosslinker for attaching compounds to sulfhydryl groups (cysteines) after conjugating the linker to hydroxyl groups on a molecule by urethane (carbamate) bonds.
Highlights:
- Maleimide forms stable thioether linkages
- Isocyanate reacts with - OH groups to form a carbamate link at pH 8.5
- Excellent tool for conjugating - OH group-containing compounds such as steroids and vitamins
- Reactive groups: maleimide and isocyanate
- Reactive toward: sulfhydryl and hydroxyl groups
Specifications
| Carboxyl-Sulfhydryl | |
| PMPI | |
| No | |
| Upon receipt store at 4°C protected from moisture. | |
| Ambient | |
| Chemical Labeling | |
| Maleimide, Isocyanate | |
| Solid | |
| DMF, DMSO | |
| No |
| No | |
| 307.1 | |
| 8.7 Å | |
| Not determined | |
| Pierce™ | |
| Heterobifunctional | |
| Short (<10 Å) | |
| 50 mg | |
| Standard | |
| Crosslinker |
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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