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Thermo Scientific™ PMPI (p-maleimidophenyl isocyanate)
Short (8.7A) hydroxyl-to-sulfhydryl crosslinker; isocyanate and maleimide groups; label -OH by urethane bonds for conjugation to cysteines by thioether bonds.
Brand: Thermo Scientific™ 28100
This item is not returnable.
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Description
Thermo Scientific™ Pierce PMPI is a maleimide-and-isocyanate crosslinker for attaching compounds to sulfhydryl groups (cysteines) after conjugating the linker to hydroxyl groups on a molecule by urethane (carbamate) bonds.
Highlights:
- Maleimide forms stable thioether linkages
- Isocyanate reacts with - OH groups to form a carbamate link at pH 8.5
- Excellent tool for conjugating - OH group-containing compounds such as steroids and vitamins
- Reactive groups: maleimide and isocyanate
- Reactive toward: sulfhydryl and hydroxyl groups
Specifications
Carboxyl-Sulfhydryl | |
PMPI | |
No | |
Upon receipt store at 4°C protected from moisture. | |
Ambient | |
Chemical Labeling | |
Maleimide, Isocyanate | |
Solid | |
DMF, DMSO | |
No |
No | |
307.1 | |
8.7 Å | |
Not determined | |
Pierce™ | |
Heterobifunctional | |
Short (<10 Å) | |
50 mg | |
Standard | |
Crosslinker |
For Research Use Only. Not for use in diagnostic procedures.