Thermo Scientific™ MT(PEG)4 Methyl-PEG-Thiol Compound

Description

Thermo Scientific™ Pierce MT(PEG)4, or methyl-PEG4-thiol, is a methyl- and sulfhydryl-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic particles.

MT(PEG)4 is monodentate thiol-terminated and methyl pegylation reagent. The PEG compound has a defined molecular weight and spacer length and is useful for modifying surfaces such quantum dots, self-assembled monolayers and magnetic particles. Functionalization of solid surfaces with polyethylene glycol spacers such as this one significantly reduces nonspecific protein binding.

Highlights:

• Metal-binding – terminal monodentate thiol reacts spontaneously with gold surfaces through dative binding

• Methyl – terminal methyl group is unreactive, the primary function of this compound being to coat quantum dot and other surfaces to reduce nonspecific binding in assays

• Polyethylene glycol – PEG groups are flexible, non-immunogenic, hydrophilic, and significantly reduce nonspecific binding of surfaces for protein methods

• Spacer arm – four-unit PEG spacer makes compound nearly 16 angstroms long

Specifications:

• Alternative name: Methyl-PEG4-Thiol
• Chemical name: 2,5,8,11-tetraoxatridecane-13-thiol
• Chemical formula: C9H20O4S
• Molecular weight: 224.32
• Spacer arm: 15.8 angstroms
• Form: clear colorless to light yellow liquid
• Solubility: dissolve in DMSO or DMF for use