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Thermo Scientific™ LC-SMCC (succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate))
Crosslink amines to sulfhydryls with this long crosslinker composed of NHS-ester and maleimide groups at ends of a stabilizing cyclohexane-containing, 15-atom spacer arm.
Brand: Thermo Scientific™ 22362
This item is not returnable.
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Description
Thermo Scientific™ Pierce LC-SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long cyclohexane-stabilized spacer arm (16.2 Ås)
Highlights:
- Ideal for coupling enzymes to antibodies as both enzyme activity and antibody specificity can be preserved after coupling
- Cyclohexane-containing spacer stabilizes the maleimide group
- Useful for the preparation of stable maleimide-activated proteins
- Reactive groups: NHS ester and maleimide
- Reactive toward: amino and sulfhydryl groups
Specifications
Amine-Sulfhydryl | |
LC-SMCC | |
No | |
Upon receipt store desiccated at 4°C. | |
Ambient | |
Chemical Labeling | |
Maleimide, NHS Ester | |
Solid | |
DMF, DMSO | |
No |
No | |
447.48 | |
16.2 Å | |
Yes | |
Pierce™ | |
Heterobifunctional | |
Medium (10 to 30 Å) | |
50 mg | |
Standard | |
Crosslinker |
For Research Use Only. Not for use in diagnostic procedures.