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Thermo Scientific™ LC-SMCC (succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate))

Crosslink amines to sulfhydryls with this long crosslinker composed of NHS-ester and maleimide groups at ends of a stabilizing cyclohexane-containing, 15-atom spacer arm.

Brand:  Thermo Scientific™ 22362

Product Code. 11831305

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Description

Description

Thermo Scientific™ Pierce LC-SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long cyclohexane-stabilized spacer arm (16.2 Ås)

Highlights:

  • Ideal for coupling enzymes to antibodies as both enzyme activity and antibody specificity can be preserved after coupling
  • Cyclohexane-containing spacer stabilizes the maleimide group
  • Useful for the preparation of stable maleimide-activated proteins
  • Reactive groups: NHS ester and maleimide
  • Reactive toward: amino and sulfhydryl groups
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Amine-Sulfhydryl
LC-SMCC
No
Upon receipt store desiccated at 4°C.
Ambient
Chemical Labeling
Maleimide, NHS Ester
Solid
DMF, DMSO
No
No
447.48
16.2 Å
Yes
Pierce™
Heterobifunctional
Medium (10 to 30 Å)
50 mg
Standard
Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.