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Thermo Scientific™ DMP (dimethyl pimelimidate)
Crosslink amines to amines with dimethyl pimelimidate (CAS 58537-94-3); composed of imidoester groups and a membrane-permeable, 7-atom spacer arm.
Brand: Thermo Scientific™ 21666
Description
Thermo Scientific™ Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm.
Highlights:
- Water-soluble
- Rapid reaction with amines at alkaline pH values (pH 8-10)
- Amidine bond retains net charge character of protein
- Reversible at high pH values
- Reactive groups: imidoester (homobifunctional)
- Reactive toward: amino groups
Specifications
Amine-Amine | |
DMP | |
No | |
Upon receipt store desiccated at 4°C. | |
Ambient | |
Chemical Labeling | |
Imidoester | |
Powder | |
Water | |
Yes |
No | |
259.17 | |
9.2 Å | |
Yes | |
Pierce™ | |
Homobifunctional | |
Short (<10 Å) | |
50 mg | |
Standard | |
Crosslinker |
Safety and Handling
- DMP (dimethyl pimelimidate)
Signal Word
- Warning
Hazard Category
- Skin corrosion/irritation Category 2
Hazard Statement
- H315-Causes skin irritation.
Precautionary Statement
- P260-Do not breathe dust/fume/gas/mist/vapours/spray.
- P264-Wash hands thoroughly after handling.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Supplemental information
- MIXTURE LIST-Contains : dimethyl heptane-1,7-diimidate dihydrochloride
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For Research Use Only. Not for use in diagnostic procedures.